RapamycinFungusV1, Main, Exploration, bibRecord, 001605

Nuclear translocation of Gln3 in response to nutrient signals requires Golgi-to-endosome trafficking in Saccharomyces cerevisiae.

Identifieur interne : 001605 ( Main/Exploration ); précédent : 001604; suivant : 001606

Nuclear translocation of Gln3 in response to nutrient signals requires Golgi-to-endosome trafficking in Saccharomyces cerevisiae.

Auteurs : Rekha Puria [États-Unis] ; Sara A. Zurita-Martinez ; Maria E. Cardenas

Source :

Proceedings of the National Academy of Sciences of the United States of America [ 1091-6490 ] ; 2008.

RBID : pubmed:18443284

Descripteurs français

English descriptors

KwdEn :
- Active Transport, Cell Nucleus (MeSH), Cell Membrane (metabolism), Cell Nucleus (metabolism), Endosomes (metabolism), Gene Expression Regulation, Fungal (MeSH), Genes, Fungal (MeSH), Golgi Apparatus (metabolism), Models, Biological (MeSH), Mutation (MeSH), Nitrogen (MeSH), Repressor Proteins (metabolism), Repressor Proteins (physiology), Saccharomyces cerevisiae (metabolism), Saccharomyces cerevisiae Proteins (metabolism), Saccharomyces cerevisiae Proteins (physiology), Subcellular Fractions (metabolism), Transcription Factors (metabolism), Transcription Factors (physiology), Transcriptional Activation (MeSH), Vesicular Transport Proteins (metabolism).
MESH :
- chemical , metabolism : Repressor Proteins, Saccharomyces cerevisiae Proteins, Transcription Factors, Vesicular Transport Proteins.
- chemical , physiology : Repressor Proteins, Saccharomyces cerevisiae Proteins, Transcription Factors.
- chemical : Nitrogen.
- metabolism : Cell Membrane, Cell Nucleus, Endosomes, Golgi Apparatus, Saccharomyces cerevisiae, Subcellular Fractions.
- Active Transport, Cell Nucleus, Gene Expression Regulation, Fungal, Genes, Fungal, Models, Biological, Mutation, Transcriptional Activation.

Abstract

The yeast Saccharomyces cerevisiae has developed specialized mechanisms that enable growth on suboptimal nitrogen sources. Exposure of yeast cells to poor nitrogen sources or treatment with the Tor kinase inhibitor rapamycin elicits activation of Gln3 and transcription of nitrogen catabolite-repressed (NCR) genes whose products function in scavenging and metabolizing nitrogen. Here, we show that mutations in class C and D Vps components, which mediate Golgi-to-endosome vesicle transport, impair nuclear translocation of Gln3, NCR gene activation, and growth in poor nitrogen sources. In nutrient-replete conditions, a significant fraction of Gln3 is peripherally associated with light membranes and partially colocalizes with Vps10-containing foci. These results reveal a role for Golgi-to-endosome vesicular trafficking in TORC1-controlled nuclear translocation of Gln3 and support a model in which Tor-mediated signaling in response to nutrient cues occurs in these compartments. These findings have important implications for nutrient sensing and growth control via mTor pathways in metazoans.

DOI: 10.1073/pnas.0801087105
PubMed: 18443284
PubMed Central: PMC2438226

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 001616
to stream Main, to step Curation: 001616

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Nuclear translocation of Gln3 in response to nutrient signals requires Golgi-to-endosome trafficking in Saccharomyces cerevisiae.</title>
<author><name sortKey="Puria, Rekha" sort="Puria, Rekha" uniqKey="Puria R" first="Rekha" last="Puria">Rekha Puria</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710</wicri:regionArea>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Zurita Martinez, Sara A" sort="Zurita Martinez, Sara A" uniqKey="Zurita Martinez S" first="Sara A" last="Zurita-Martinez">Sara A. Zurita-Martinez</name>
</author>
<author><name sortKey="Cardenas, Maria E" sort="Cardenas, Maria E" uniqKey="Cardenas M" first="Maria E" last="Cardenas">Maria E. Cardenas</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2008">2008</date>
<idno type="RBID">pubmed:18443284</idno>
<idno type="pmid">18443284</idno>
<idno type="doi">10.1073/pnas.0801087105</idno>
<idno type="pmc">PMC2438226</idno>
<idno type="wicri:Area/Main/Corpus">001616</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">001616</idno>
<idno type="wicri:Area/Main/Curation">001616</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">001616</idno>
<idno type="wicri:Area/Main/Exploration">001616</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Nuclear translocation of Gln3 in response to nutrient signals requires Golgi-to-endosome trafficking in Saccharomyces cerevisiae.</title>
<author><name sortKey="Puria, Rekha" sort="Puria, Rekha" uniqKey="Puria R" first="Rekha" last="Puria">Rekha Puria</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710</wicri:regionArea>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Zurita Martinez, Sara A" sort="Zurita Martinez, Sara A" uniqKey="Zurita Martinez S" first="Sara A" last="Zurita-Martinez">Sara A. Zurita-Martinez</name>
</author>
<author><name sortKey="Cardenas, Maria E" sort="Cardenas, Maria E" uniqKey="Cardenas M" first="Maria E" last="Cardenas">Maria E. Cardenas</name>
</author>
</analytic>
<series><title level="j">Proceedings of the National Academy of Sciences of the United States of America</title>
<idno type="eISSN">1091-6490</idno>
<imprint><date when="2008" type="published">2008</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Active Transport, Cell Nucleus (MeSH)</term>
<term>Cell Membrane (metabolism)</term>
<term>Cell Nucleus (metabolism)</term>
<term>Endosomes (metabolism)</term>
<term>Gene Expression Regulation, Fungal (MeSH)</term>
<term>Genes, Fungal (MeSH)</term>
<term>Golgi Apparatus (metabolism)</term>
<term>Models, Biological (MeSH)</term>
<term>Mutation (MeSH)</term>
<term>Nitrogen (MeSH)</term>
<term>Repressor Proteins (metabolism)</term>
<term>Repressor Proteins (physiology)</term>
<term>Saccharomyces cerevisiae (metabolism)</term>
<term>Saccharomyces cerevisiae Proteins (metabolism)</term>
<term>Saccharomyces cerevisiae Proteins (physiology)</term>
<term>Subcellular Fractions (metabolism)</term>
<term>Transcription Factors (metabolism)</term>
<term>Transcription Factors (physiology)</term>
<term>Transcriptional Activation (MeSH)</term>
<term>Vesicular Transport Proteins (metabolism)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Activation de la transcription (MeSH)</term>
<term>Appareil de Golgi (métabolisme)</term>
<term>Azote (MeSH)</term>
<term>Endosomes (métabolisme)</term>
<term>Facteurs de transcription (métabolisme)</term>
<term>Facteurs de transcription (physiologie)</term>
<term>Fractions subcellulaires (métabolisme)</term>
<term>Gènes fongiques (MeSH)</term>
<term>Membrane cellulaire (métabolisme)</term>
<term>Modèles biologiques (MeSH)</term>
<term>Mutation (MeSH)</term>
<term>Noyau de la cellule (métabolisme)</term>
<term>Protéines de Saccharomyces cerevisiae (métabolisme)</term>
<term>Protéines de Saccharomyces cerevisiae (physiologie)</term>
<term>Protéines de répression (métabolisme)</term>
<term>Protéines de répression (physiologie)</term>
<term>Protéines du transport vésiculaire (métabolisme)</term>
<term>Régulation de l'expression des gènes fongiques (MeSH)</term>
<term>Saccharomyces cerevisiae (métabolisme)</term>
<term>Transport nucléaire actif (MeSH)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Repressor Proteins</term>
<term>Saccharomyces cerevisiae Proteins</term>
<term>Transcription Factors</term>
<term>Vesicular Transport Proteins</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="physiology" xml:lang="en"><term>Repressor Proteins</term>
<term>Saccharomyces cerevisiae Proteins</term>
<term>Transcription Factors</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en"><term>Nitrogen</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Cell Membrane</term>
<term>Cell Nucleus</term>
<term>Endosomes</term>
<term>Golgi Apparatus</term>
<term>Saccharomyces cerevisiae</term>
<term>Subcellular Fractions</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Appareil de Golgi</term>
<term>Endosomes</term>
<term>Facteurs de transcription</term>
<term>Fractions subcellulaires</term>
<term>Membrane cellulaire</term>
<term>Noyau de la cellule</term>
<term>Protéines de Saccharomyces cerevisiae</term>
<term>Protéines de répression</term>
<term>Protéines du transport vésiculaire</term>
<term>Saccharomyces cerevisiae</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Facteurs de transcription</term>
<term>Protéines de Saccharomyces cerevisiae</term>
<term>Protéines de répression</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Active Transport, Cell Nucleus</term>
<term>Gene Expression Regulation, Fungal</term>
<term>Genes, Fungal</term>
<term>Models, Biological</term>
<term>Mutation</term>
<term>Transcriptional Activation</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Activation de la transcription</term>
<term>Azote</term>
<term>Gènes fongiques</term>
<term>Modèles biologiques</term>
<term>Mutation</term>
<term>Régulation de l'expression des gènes fongiques</term>
<term>Transport nucléaire actif</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The yeast Saccharomyces cerevisiae has developed specialized mechanisms that enable growth on suboptimal nitrogen sources. Exposure of yeast cells to poor nitrogen sources or treatment with the Tor kinase inhibitor rapamycin elicits activation of Gln3 and transcription of nitrogen catabolite-repressed (NCR) genes whose products function in scavenging and metabolizing nitrogen. Here, we show that mutations in class C and D Vps components, which mediate Golgi-to-endosome vesicle transport, impair nuclear translocation of Gln3, NCR gene activation, and growth in poor nitrogen sources. In nutrient-replete conditions, a significant fraction of Gln3 is peripherally associated with light membranes and partially colocalizes with Vps10-containing foci. These results reveal a role for Golgi-to-endosome vesicular trafficking in TORC1-controlled nuclear translocation of Gln3 and support a model in which Tor-mediated signaling in response to nutrient cues occurs in these compartments. These findings have important implications for nutrient sensing and growth control via mTor pathways in metazoans.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">18443284</PMID>
<DateCompleted><Year>2008</Year>
<Month>06</Month>
<Day>24</Day>
</DateCompleted>
<DateRevised><Year>2018</Year>
<Month>11</Month>
<Day>13</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1091-6490</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>105</Volume>
<Issue>20</Issue>
<PubDate><Year>2008</Year>
<Month>May</Month>
<Day>20</Day>
</PubDate>
</JournalIssue>
<Title>Proceedings of the National Academy of Sciences of the United States of America</Title>
<ISOAbbreviation>Proc Natl Acad Sci U S A</ISOAbbreviation>
</Journal>
<ArticleTitle>Nuclear translocation of Gln3 in response to nutrient signals requires Golgi-to-endosome trafficking in Saccharomyces cerevisiae.</ArticleTitle>
<Pagination><MedlinePgn>7194-9</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1073/pnas.0801087105</ELocationID>
<Abstract><AbstractText>The yeast Saccharomyces cerevisiae has developed specialized mechanisms that enable growth on suboptimal nitrogen sources. Exposure of yeast cells to poor nitrogen sources or treatment with the Tor kinase inhibitor rapamycin elicits activation of Gln3 and transcription of nitrogen catabolite-repressed (NCR) genes whose products function in scavenging and metabolizing nitrogen. Here, we show that mutations in class C and D Vps components, which mediate Golgi-to-endosome vesicle transport, impair nuclear translocation of Gln3, NCR gene activation, and growth in poor nitrogen sources. In nutrient-replete conditions, a significant fraction of Gln3 is peripherally associated with light membranes and partially colocalizes with Vps10-containing foci. These results reveal a role for Golgi-to-endosome vesicular trafficking in TORC1-controlled nuclear translocation of Gln3 and support a model in which Tor-mediated signaling in response to nutrient cues occurs in these compartments. These findings have important implications for nutrient sensing and growth control via mTor pathways in metazoans.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Puria</LastName>
<ForeName>Rekha</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Zurita-Martinez</LastName>
<ForeName>Sara A</ForeName>
<Initials>SA</Initials>
</Author>
<Author ValidYN="Y"><LastName>Cardenas</LastName>
<ForeName>Maria E</ForeName>
<Initials>ME</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<GrantList CompleteYN="Y"><Grant><GrantID>R01 CA114107</GrantID>
<Acronym>CA</Acronym>
<Agency>NCI NIH HHS</Agency>
<Country>United States</Country>
</Grant>
<Grant><GrantID>CA114107</GrantID>
<Acronym>CA</Acronym>
<Agency>NCI NIH HHS</Agency>
<Country>United States</Country>
</Grant>
</GrantList>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D052061">Research Support, N.I.H., Extramural</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2008</Year>
<Month>04</Month>
<Day>28</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Proc Natl Acad Sci U S A</MedlineTA>
<NlmUniqueID>7505876</NlmUniqueID>
<ISSNLinking>0027-8424</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="C071664">GLN3 protein, S cerevisiae</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="C087335">PEP1 protein, S cerevisiae</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D012097">Repressor Proteins</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D029701">Saccharomyces cerevisiae Proteins</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D014157">Transcription Factors</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D033921">Vesicular Transport Proteins</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>N762921K75</RegistryNumber>
<NameOfSubstance UI="D009584">Nitrogen</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<CommentsCorrectionsList><CommentsCorrections RefType="CommentIn"><RefSource>Proc Natl Acad Sci U S A. 2008 May 20;105(20):7111-2</RefSource>
<PMID Version="1">18474868</PMID>
</CommentsCorrections>
</CommentsCorrectionsList>
<MeshHeadingList><MeshHeading><DescriptorName UI="D021581" MajorTopicYN="N">Active Transport, Cell Nucleus</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002462" MajorTopicYN="N">Cell Membrane</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002467" MajorTopicYN="N">Cell Nucleus</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011992" MajorTopicYN="N">Endosomes</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015966" MajorTopicYN="Y">Gene Expression Regulation, Fungal</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005800" MajorTopicYN="N">Genes, Fungal</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006056" MajorTopicYN="N">Golgi Apparatus</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008954" MajorTopicYN="N">Models, Biological</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009154" MajorTopicYN="N">Mutation</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009584" MajorTopicYN="N">Nitrogen</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012097" MajorTopicYN="N">Repressor Proteins</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
<QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012441" MajorTopicYN="N">Saccharomyces cerevisiae</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D029701" MajorTopicYN="N">Saccharomyces cerevisiae Proteins</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
<QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013347" MajorTopicYN="N">Subcellular Fractions</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014157" MajorTopicYN="N">Transcription Factors</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
<QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015533" MajorTopicYN="N">Transcriptional Activation</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D033921" MajorTopicYN="N">Vesicular Transport Proteins</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2008</Year>
<Month>4</Month>
<Day>30</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2008</Year>
<Month>6</Month>
<Day>25</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2008</Year>
<Month>4</Month>
<Day>30</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">18443284</ArticleId>
<ArticleId IdType="pii">0801087105</ArticleId>
<ArticleId IdType="doi">10.1073/pnas.0801087105</ArticleId>
<ArticleId IdType="pmc">PMC2438226</ArticleId>
</ArticleIdList>
<ReferenceList><Reference><Citation>Traffic. 2001 Jul;2(7):476-86</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11422941</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 2000 Nov 17;275(46):35727-33</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10940301</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Gene. 2002 May 15;290(1-2):1-18</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12062797</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 2002 Oct 4;277(40):37559-66</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12140287</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Biol Cell. 2003 Mar;14(3):1204-20</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12631735</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Cell Biol. 2003 Apr 28;161(2):333-47</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12719473</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 2003 May 9;278(19):16878-86</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12624103</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 2004 Mar 12;279(11):10270-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14679193</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 2004 Apr 9;279(15):14752-62</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14736892</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Biol Cell. 2004 Nov;15(11):5075-91</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15356264</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Genes Genet Syst. 2005 Oct;80(5):325-43</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16394584</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>FEMS Yeast Res. 2006 Mar;6(2):218-29</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16487345</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Methods Enzymol. 1991;194:428-53</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2005802</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Biol Cell. 1992 Dec;3(12):1389-402</Citation>
<ArticleIdList><ArticleId IdType="pubmed">1493335</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 1994 Apr 22;264(5158):566-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7909170</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Eur J Cell Biol. 1994 Dec;65(2):305-18</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7720726</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>EMBO J. 1995 Dec 1;14(23):5892-907</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8846782</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Genes Dev. 1996 Feb 1;10(3):279-88</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8595879</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Biol Cell. 1997 May;8(5):871-95</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9168472</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Yeast. 1998 Jul;14(10):953-61</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9717241</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 1999 Feb 16;96(4):1498-503</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9990052</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Yeast. 1999 Oct;15(14):1541-53</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10514571</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Biochim Biophys Acta. 2005 Jul 10;1744(3):438-54</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15913810</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Cell. 2005 Jul 1;19(1):15-26</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15989961</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 2001 Aug 24;276(34):32136-44</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11408486</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Biol Cell. 2006 Mar;17(3):1344-53</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16407402</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Cell Biol. 2006 Apr;26(8):3243-55</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16581797</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Cell Biol. 2006 Jul;8(7):657-67</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16732272</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell. 2006 Jul 14;126(1):191-203</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16839886</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>FEMS Yeast Res. 2006 Aug;6(5):777-91</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16879428</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>EMBO J. 2006 Aug 9;25(15):3546-55</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16874307</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2006 Nov 21;103(47):17840-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17095607</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Biol Cell. 2007 Mar;18(3):1073-82</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17215520</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Biol Cell. 2007 Aug;18(8):2779-94</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17507646</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Genetics. 2007 Aug;176(4):2139-50</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17565946</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Opin Microbiol. 2008 Apr;11(2):153-60</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18396450</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 1999 Dec 9;402(6762):689-92</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10604478</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Genes Dev. 1999 Dec 15;13(24):3271-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10617575</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Biol Cell. 2000 Jan;11(1):305-23</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10637310</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Biol Cell. 2000 Feb;11(2):613-26</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10679018</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Genetics. 2000 Sep;156(1):105-22</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10978279</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 2000 Nov 24;275(47):37011-20</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10973982</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>États-Unis</li>
</country>
<region><li>Caroline du Nord</li>
</region>
</list>
<tree><noCountry><name sortKey="Cardenas, Maria E" sort="Cardenas, Maria E" uniqKey="Cardenas M" first="Maria E" last="Cardenas">Maria E. Cardenas</name>
<name sortKey="Zurita Martinez, Sara A" sort="Zurita Martinez, Sara A" uniqKey="Zurita Martinez S" first="Sara A" last="Zurita-Martinez">Sara A. Zurita-Martinez</name>
</noCountry>
<country name="États-Unis"><region name="Caroline du Nord"><name sortKey="Puria, Rekha" sort="Puria, Rekha" uniqKey="Puria R" first="Rekha" last="Puria">Rekha Puria</name>
</region>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Bois/explor/RapamycinFungusV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001605 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001605 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Bois
   |area=    RapamycinFungusV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:18443284
   |texte=   Nuclear translocation of Gln3 in response to nutrient signals requires Golgi-to-endosome trafficking in Saccharomyces cerevisiae.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:18443284" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a RapamycinFungusV1

This area was generated with Dilib version V0.6.38.
Data generation: Thu Nov 19 21:55:41 2020. Site generation: Thu Nov 19 22:00:39 2020

	Serveur d'exploration sur la rapamycine et les champignons
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur la rapamycine et les champignons

Nuclear translocation of Gln3 in response to nutrient signals requires Golgi-to-endosome trafficking in Saccharomyces cerevisiae.

Nuclear translocation of Gln3 in response to nutrient signals requires Golgi-to-endosome trafficking in Saccharomyces cerevisiae.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki